Dr Garrick Don (Respiratory and Sleep Medicine Specialist)

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Name
Dr Garrick William Don
Qualifications
MBBS University of Sydney 2005
FRACP 2011
Occupation
Respiratory and Sleep Medicine Specialist
Gender
Male
Medical Specialties
Respiratory and Sleep Medicine

Dr Garrick Don is a Respiratory & Sleep Physician, and holds the position of Staff Specialist at Royal North Shore Hospital, with additional admitting and consulting rights at North Shore Private Hospital and the Sydney Adventist Hospital.

Dr Garrick Don 's current clinical practice covers a wide range of disorders including Airways Disease (COPD, emphysema, asthma and bronchiectasis), Interstitial Lung Disease, Pulmonary Hypertension, Lung Cancer, Tuberculosis, Bronchoscopy and Sleep Medicine.

Dr Don has interests in novel methods of treatment for obstructive sleep apnoea, tuberculosis and applied respiratory physiology.

Hospital Affiliations
North Shore Private Hospital
Royal Prince Alfred Hospital
Sydney Adventist Hospital
Royal Prince Alfred Hospital
Affiliated Clinics
North Shore Respiratory and Sleep
Affiliated Organisations
The Thoracic Society of Australia and New Zealand (TSANZ)
Lung Foundation Australia
Medical Conditions
Chronic obstructive pulmonary disease
Asthma
Interstitial lung disease
Lung cancer
Pulmonary hypertension
Tuberculosis
Obstructive sleep apnea
Medical Interventions
Bronchoscopy
Topics
Sleep Medicine

Practice Locations

Sydney

North Shore Respiratory & Sleep
North Shore Private Hospital
Suite 2 Level 5
St Leonards NSW 2065 
Australia
02 9966 4600
02 9966 4688

Publications

  • Influence of sleep state on frequency of swallowing, apnea, and arousal in human infants. Influence of sleep state on frequency of swallowing, apnea, and arousal in human infants. J Appl Physiol (1985) 2003;94:2456-64. http://www.ncbi.nlm.nih.gov/pubmed/12576405 Abstract: Apnea and arousal are modulated with sleep stage, and swallowing may interfere with respiratory rhythm in infants. We hypothesized that swallowing itself would display interaction with sleep state. Concurrent polysomnography and measurement of swallowing allowed time-matched analysis of 3,092 swallows, 482 apneas, and 771 arousals in 17 infants aged 1-34 wk. The mean rates of swallowing, apnea, and arousal were significantly different, being 23.3 +/- 8.5, 9.4 +/- 8.8, and 15.5 +/- 10.6 h(-1), respectively (P < 0.001 ANOVA). Swallows occurred before 25.2 +/- 7.9% and during 74.8 +/- 6.3% of apneas and before 39.8 +/- 6.0% and during 60.2 +/- 6.0% of arousals. The frequencies of apneas and arousals were both strongly influenced by sleep state (active sleep > indeterminate > quiet sleep, P < 0.001), whether or not the events coincided with swallowing, but swallowing rate showed minimal independent interaction with sleep state. Interactions between swallowing and sleep state were predominantly influenced by the coincidence of swallowing with apnea or arousal.
  • Site and mechanics of spontaneous, sleep-associated obstructive apnea in infants. Site and mechanics of spontaneous, sleep-associated obstructive apnea in infants. J Appl Physiol (1985) 2000;89:2453-62. http://www.ncbi.nlm.nih.gov/pubmed/11090602 Abstract: To examine the mechanics of infantile obstructive sleep apnea (OSA), airway pressures were measured using a triple-lumen catheter in 19 infants (age 1-36 wk), with concurrent overnight polysomnography. Catheter placement was guided by correlations between measurements of magnetic resonance images and body weight of 70 infants. The level of spontaneous obstruction was palatal in 52% and retroglossal in 48% of all events. Palatal obstruction predominated in infants treated for OSA (80% of events), compared with 38.6% from infants with infrequent events (P = 0.02). During obstructive events, successive respiratory efforts increased in amplitude (mean intrathoracic pressures -11.4, -15.0, and -20.4 cmH(2)O; ANOVA, P < 0.05), with arousal after only 29% of the obstructive and mixed apneas. The soft palate is commonly involved in the upper airway obstruction of infants suffering OSA. Postterm, infant responses to upper airway obstruction are intermediate between those of preterm infants and older children, with infrequent termination by arousal but no persisting "upper airway resistance" and respiratory efforts exceeding baseline during the event.