Lambert–Eaton myasthenic syndrome
Lambert–Eaton myasthenic syndrome (LEMS also Lambert–Eaton syndrome or Eaton–Lambert syndrome) is a rare autoimmune disorder that is characterized by muscle weakness of the limbs. It is the result of an autoimmune reaction in which antibodies are formed against presynaptic voltage-gated calcium channels and likely other nerve terminal proteins in the neuromuscular junction (the connection between nerves and the muscle that they supply). The prevalence is 3.4 cases per million.
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