Amyloidosis
In medicine amyloidosis refers to a variety of conditions wherein normally soluble proteins become insoluble and are deposited in the extracellular space of various organs or tissues disrupting normal function. The insoluble fibrous protein aggregates that develop in amyloidosis are known as amyloids. They result from a change in the protein's secondary structure which causes the protein to take on a particular aggregated insoluble form similar to the beta-pleated sheet.
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