Biliary atresia

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Biliary atresia also known as extrahepatic ductopenia and progressive obliterative cholangiopathy is a congenital or acquired disease of the liver and one of the principal forms of chronic rejection of a transplanted liver allograft. As a birth defect in newborn infants it has an occurrence of 1/10000 to 1/15000 cases in live births in the United States. In the congenital form the common bile duct between the liver and the small intestine is blocked or absent.
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https://en.wikipedia.org/wiki/Biliary atresia
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